Abstract 87: The Safety of Preoperative Versus Postoperative Enoxaparin Chemoprophylaxis in Autologous Microsurgical Breast Reconstruction

RESULTS: Of the 10,784 patients who underwent immediate prosthesis-based reconstruction, 5,516 (51%) filled antibiotic prescriptions. These patients were equally likely to develop an infection (OR 1.0 95%CI(0.85–1.18); p=0.98) or require explantation (OR 0.96 95%CI(0.80– 1.15); p=0.64) compared to those who did not. There was no difference in the likelihood of infection or explantation based on duration of antibiotics of 1–5 days (OR 0.85 95%CI(0.59–1.08); p=0.08), 6–10 days (OR 1.01 95%CI(0.90–1.14); p=0.84), or greater than 10 days (OR 0.97 95%CI(0.81–1.16); p=0.74). Comorbidities significantly increased the risk of infection and explantation (p<.05).